Tuesday, September 16, 2008

Breast cancer vaccine kills tumors in mice

DETROIT, Sept. 15 (UPI) -- Wayne State University researchers say a breast cancer vaccine completely eliminated HER2-positive tumors in mice -- without any toxicity.

The study, published in the journal Cancer Research, suggests the vaccine could treat women with HER2-positive, treatment-resistant cancer or help prevent cancer recurrence. The researchers also say it might potentially be used in cancer-free women to prevent initial development of these tumors.

"The immune response against HER2-positive receptors we saw in this study is powerful, and works even in tumors that are resistant to current therapies," lead investigator Wei-Zen Wei says in a statement.

"The vaccine could potentially eliminate the need to even use these therapies."


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