From the BBC:
Three of the sisters and one brother have only ever walked on two hands and two feet, but another sister alternates between a bipedal and quadrupedal gait. Another brother walks on two feet all the time, but only with difficulty.
The siblings live with their parents and five other brothers and sisters. They were born with what looks like a form of brain damage.
MRI scans seem to show that they have a form of cerebellar ataxia, which affects balance and coordination.
Video here.
I'm not totally buying this as a genetic scenario, but it's interesting nonetheless.
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